Communications Essay Example | Topics and Well Written Essays - 250 words

Communications - Essay Example Ease of use and included software installation are other selling points touted on the product web page. This system would prove effective in corrections facilities, which would be expected since this is the target market segment for the product. The Comfort Contego is a communication system that is promoted as a device for hearing enhancement and assistance. On a webpage on which the device is sold (TecEar LLC, 2011), the Comfort Contego is described as a high definition wireless FM system that uses an encrypted signal on securely coded channels. These features have several areas of use (lectures, at school or work, entertainment and telephone audio enhancement), but the secure nature of the system makes it an ideal hearing assistance device for courtrooms. The technology applied in this device is a focal point in the marketing of the Comfort Contego, with features such as the FM transmission system, integration with hearing aids, and the presence of two microphones being advertised as technical benefits associated with the device. If the Comfort Contego communication system is as secure as is advertised, then it would be ideal for sensitive applications such as courtroom hearing

Personal statement for MSA Essay Example for Free

Personal statement for MSA Essay If to use a single word describing myself, I would say, integrity, which means a mixture of various qualities and views from different cultures and working experiences. My hometown, **, which was a harbor and now the booming coastal metropolis, brought me a grant view of how fast the speed of globalization is. Meanwhile, the dramatic economic growth of the city enlightened me for seeking and digging qualities that would match its future. As a result, I went to the other hemisphere of the world, United States, which was described as the most developed country, to ursue my Bachelors degree in business finance. Through the Joyful college life with diligent study in coursework and a verity of academic club taking, on a sunny day, Aug 28th, 2011, I obtained my Bachelors degree from Ohio State University with Magna Cum Laude. Moreover, my 3. 86 specialization GPA makes me a competitive individual among my schoolmates. Seeking a Job is not a fun thing, especially for a recent graduate and in the economic downturn, though, I still keep myself with the optimistic attitude and enough confidence in this whole process. Before my first official Job was offered, I gathered a erious of experiences from different positions: work as a part-time tax processor in a credited accounting firm, ***as a par-time bookkeeper in an entertainment company, Prime Social Group; and, even work as a sales associate in the subsidy of Gap, Inc, Old Navvy. These experiences, which supposed not decent enough for an honor graduate, told me how hard life could be, and made me more perseverant. After scatted out hundreds of my resume, and Joined tens something interview, I got my first official Job offer: financial analyst in ***, a healthcare financial consulting firm. My frank peers introduced me with some models and methodologies the company uses for a number of hospitals and nursing homes. Though some of the analysis sounds hard at the first glance, I still believe my personal qualities and skills, for example, I am a profound thinker that is knowledgeable of computer language Access SQL and Excel, could help me to conquer them. I penetrated myself in calculating and analyzing those Key Performance Indexes and valuation models. After I submitted my first report, though its not perfect, my supervisor, ***, comment this as, Its amazing or a recent graduate with little analysis experiences to create the model and fgure such a lot of crucial points out. Besides, even the principle of the team,***, who used to be a professor in ***, appreciated my work ethic. Those words did stimulate me for a while. Experiences in ** extended my view of what consulting firms could help for clients. Consulting are not limit in investment finance taking care of stocks and bonds, IPO issuing, etc, more than that, lots of consulting firms are doing analysis on a corporate base, thus, much accounting knowledge involved. I also remember Andrew said to me wou d be essential tor getting a senior level position in financial consulting firm, and, a Master of Accounting would be a plus.

20th Century Essay -- essays research papers

Music written since 1900 is called twentieth century music. There have been more types and styles of music written in the twentieth century then ever before. In the twentieth century, the only limit is the composer's imagination. This great variety of musical styles reflected the diversity of life during the early twentieth century. More people were free to choose where to live, how to earn a living, and how to spend their time. The car, airplane, telephone, phonograph, movies, and radio all made the world more accessible and expanded the range of experiences. Technological developments have also had an influence on the twentieth century music, especially electronic music. Like all people, musicians have been affected by the political, economic, and social problems of twentieth century. Hitler’s rise to power in Germany in 1933 had an especially dramatic impact on the lives and careers of musicians. Many composers left Europe for the United States. These refugees made huge contributions to musical culture. One of the most significant changes in components of music that formed twentieth century music is rhythm. The modern music is full of complex rhythms and time signatures. The major reason for the increase of rhythms in twentieth century music is the development of the ballet. The second component of twentieth century music is melody. This new music moves away from the traditional melodic line that previous musical styles had developed. Modern composers have also rejected...

This is Water Summary Essay

Wallace delivered the Kenyon College commencement address that was not the typical commencement address you would normally hear at a graduation. He starts off his speech by telling a story having the idea that even the most â€Å"important realities are often the ones that are hardest to see and talk about. † He talks about living in the adult world that these soon to be graduates will enter and how it can be ere dull at times.And how learning about how to think about the choice we make in our life, the choices we make will impact our life whether it be a good impact, or a bad impact. Wallace delivers this speech (in a way to get these graduates not necessarily discouraged) giving the former students a face of reality that life is dull when you go through the same thing every day. And that when people go through the same thing â€Å"day in and day out† people tend to forget about the others around us.When forgetting about the other people around us occurs, Wallace belie ves that makes us believe that we are the â€Å"center of the universe. † This way of thinking as Wallace states is to be our â€Å"default setting† where we tend to block everyone our except for ourselves and if anyone gets in our way, then they must the ones at fault. Wallace also states, â€Å"if you really learn to pay attention, then you will know there are other options. † We have the choice to think of those other options, but we also have he choice to not think of those other options.Choosing the option to pay attention to the others around us and not be a â€Å"prisoner of our own brain† could possibly let ourselves live happier lives. Having awareness as Wallace stated, † Is unimaginably hard to do this, to stay conscious and alive In the adult world day In and day out. But, your education really Is the Job of a lifetime. † In conclusion, Wallace believes that we have choices to be aware of and to really think of the choices we make.

The Movie Django

Gary L. Willis AFRS 55T (T&[email  protected]:30) Dr. T. Hasan Johnson 02. 23. 13 Extra Credit The Movie â€Å"Django Unchained† The objective of this paper is to review some of the results of the discussion-panel’s analysis of certain aspects of this movie that relate to the Hip-Hop culture. On Thursday, February 21, 2013, I attended a panel discussion hosted by the Africana Studies Department of Fresno State University. It was conducted at the African American Museum, Fresno California. Its purpose was to evaluate this movie’s effect on us (basically Black-Americans), by analyzing elements of this movie.This movie presents Black masculinity and femininity during the 1860s slavery era of America using characters that portray slaves as childish and stupid (the Betina or D'Artagnan), violent (the Mandingo or Django), hypersexual (Sheba) and cowardly (all the black male slaves). These slavery created representations of Black masculinity (the Buck) and femininity (the Jezebel/Mulattoe) are relevant to Hip-Hop because they are the predominate characters being proffered as entertainment in the overwhelming majority of Hip-Hop videos.The stereotypical persona of â€Å"The Buck† in the videos is the Gangsta/Thug and â€Å"The Jezebel/Mulattoe† is the Bitch/Ho— both are slavery created stereotypes. The Jezebel/Mulatto (Bitch/Ho) The Buck (Gangsta/Thug) Another aspect of this movie relevant to Hip-hop culture is the word â€Å"nigger†, used incessantly in the movie, just as, its morphed version, â€Å"Nigga† is used incessantly by Hip-Hoppers, in conversation and in their videos.Since language is one of the seven essential element of all cultures, the usage of the word â€Å"nigger† was discussed by the panel and audience and as a result of this discussion, we agreed that—without the use of the word â€Å"nigger†, â€Å"Django Unchained† would not be authentic; because, in this movie, â€Å"nigger† is a descriptive term, used to describe property, e. g. a slave or slaves—with no malice intended. Here are two examples, horse or horses and house or houses—ergo, nigger or niggers.The only character that uses â€Å"nigger† other than as a description of property is Stephen (the â€Å"Uncle Tom† played by Samuel L. Jackson). He used the word â€Å"nigger† to degrade his fellow black slaves. As with the movies use of â€Å"nigger†, the same can be said about Hip-Hop videos, they would lose its authenticity without the use of the word â€Å"Nigga† because â€Å"Nigga† in Hip-hop is a descriptive turn, but unlike â€Å"nigger† it versatility. For example, it can be used describe a relationship and its meaning changes depending on who is saying it and to whom.For example, in the movie when a Slave-master says â€Å"My nigger†, it does not have the same meaning as a Gangsta/thug or Jezebel/Mulatto e in a Hip-Hop video saying, â€Å"My Nigga†. The Slave-masters are describing their property, while the Hip-Hoppers are describing their relationships. During the audience participation portion of this discussion, a young black- man in the audience (Christopher Jackson) described how much the movie upset him.He also shared with us, the extent to which it made him realize how horrible slavery was; and how much suffering his ancestors had to endure; so that he can enjoy the civil rights he has today. He said, â€Å"Now I truly appreciate my ancestors and men like Martin and Malcolm, who made the ultimate sacrifice so that I can enjoy the freedom I have today. † Personal Reflections If the motives for making â€Å"Django Unchained† are to make us aware of how much our ancestors suffered under the yoke of slavery and to make us cherish our freedom; then, Christopher Jackson’s words are a testament to this movie’s success in both endeavors!In conclusio n—I, along with many participants in this discussion, enjoyed â€Å"Django Unchained† and hope that there will be more movies made that expose the horrors of slavery, and that, also promote positive images of black men and women. ——————————————– [ 1 ]. This paper was submitted as extra credit for AFRS 27, 55T and 144 [ 2 ]. Heretofore, us, we, and our refers to Black-Americans [ 3 ]. Donald Bogle, Toms, Coons, Mulattoes, Mammies & Bucks

The Delian League essays

The Delian League essays What where the original provisions of the Delian League? How far did Athens adhere to them between 478 and 445 B.C? The Delian League (478-461) was an affiliation of Greek city-states. When faced with subjugation from Persia, they and the states in the islands in the Aegean turned towards Athens and her powerful navy for aegis and alliance. As it was led by Athens it is sometimes pejoratively referred to as the Athenian Empire. The Delian League had many provisions such as allies, an oath, finance headquarters and Synod. Athens adhered to these necessities for a certain amount of time. However they were soon contravened, so that Athens became an imperial state. Thucydides believed that there was no turning point where Athens transgressed these provisions, rather It was the actual course of events which first compelled us to increase our power to its present extent. The aims of the League were two-fold. Their first objective was to attain a short-term offensive stance, thereby attacking Persian areas in order to, as Thucydides says Compensate themselves for their losses by ravaging the territory of the King of Persia. As well as this there was a long-term offensive intention, to maintain the freedom of the Greeks and to create a defensive association to cope with future attacks. Initially the allies were independent states, they had their own particular forms of government. Conversely, rebellious states soon lost their sovereignty and became subject to Athens. Aristotle believed it was Aristides Who swore the oaths to the Ionians that they should have the same enemies and friends to confirm which they sank lumps of iron in the sea. This oath was sworn bilaterally between the Athenians and their counterparts. It was an indication that Athens was to be the hegemon and that the League was undeviating. In this respect it would therefore be seen that an apostasy is recognised as a rebellion...

buy custom Alzheimers Breakthrough Act 0f 2009 essay

buy custom Alzheimer's Breakthrough Act 0f 2009 essay Introduction Alzheimers disease is a neurological brain disorder. It is named after a German physician known as Alois Alzheimer, who first noted it in 1906 from his patient Auguste Deter. It is the most common form of dementia. Dementia literally means loss of thinking. This disease is characterized with progressive memory loss, impairment of judgment, and decline in the ability to perform routine tasks, difficulty in learning, disorientation, loss of language skills, and personality changes. The loss of brain cells ultimately leads to the failure of other systems in the body (OTA report, 1987). The Alzheimer's Breakthrough Act was enacted in 2009. The aim this act was to fund breakthroughs in Alzheimer's disease research while providing more help to caregivers and increasing public education about prevention. Policy Analysis The goals of the Alzheimer's Breakthrough Act of 2009 are captured in three titles which are clearly outlined in the policy. The first goal was to increase federal government commitment to Alzheimers research. The federal government intended to achieve this through: doubling its funding on research related to the disease; prioritizing research on the disease; having prevention initiatives; launching a national summit on Alzheimers disease and finally initiating research on Alzheimers disease care giving. The second goal was the prevention of Alzheimers disease and thus promotingpublic health. The federal government intended to achieve this through: enhanced public health activities related to cognitive health; launching Alzheimers disease public education campaign. The third major aim of this policy was to offer assistance for caregivers. These goals do not contravene any policies on public health and thus would be rendered legal (OTA report, 1987). A glance at the statistics stated in the policy at the time of its reading, show that the mechanisms that the federal government intended to adopt were the most satisfying. They were well capable even to meet the social problems that ensued in the county as a result of the Alzheimer disease. For example, the reason why there was then need to increase commitment in research and also find scientific ways to prevent or cure the disease was because a projection showed that by 2050, the number of individuals with the disease could reach 16,000,000. The mechanisms outlined at the time of the policy reading were adequate to combat the social problems that came as a result of the disease (World Health Organization, 2010). This policy cuts across all the ages affected by the Alzheimer. It considers the young who are least likely to be affected by the disease, those above 65 years and those above 85 years. It leaves no one out. It does not segregate against the rich or poor. In fact, the federal government has adopted the most socialist way of dealing with the problem. This policy promotes the general good of the society. This is because it offers a chance for all to be supported if not be treated as we all know this disease has no cure. It has no prejudice against the social or financial status of any individual. However, such a welfare policy does frequently crumble due to lack of necessary funding. This can be sidestepped by outlining and following a good financial support plan that engages the public (IOM, 2009). A look at how the policy was to be and is administered, there an obvious sense of adequacy and equity. However, this does not necessarily reflect today as score of patients have their bills not settled. Thus, though the federal government has documented intentions to take care of its entire affected population, it is not in a capacity to do so. The problem is obviously finances. From the data collected, if there is no increased funding then the policy might just crumble in the next few years. To achieve an improved quality of life among its targeted population, the federal government may want to seek more funding through other channels. One of the underlying values captured in this document is commitment. We see a nation committed to give life to it its citizens. There are careful, well laid out implementation strategies mentioned which if well exploited would be very beneficial. The target population though large and increasing by the day, the federal government has tried to met it with a higher number of staff. This value is well in line with the very essence of social justice. There is also an aspect of socialism, a political ideology, adopted in this policy. And thus far the government has put in place an estimated funding of up to the tne of $2 billion to meet it. The greatest befit from this policy is to them that are affected. It is not to the wealthy class alone but also to the poor. These results are part of that which this research sought to achieve. There is no result whatsoever unintended. Political feasibility Alzheimer's Breakthrough Act 0f 2009 has had a wide range of support in the American community .The support has come from the government officials, the public especially relatives and care takers of the patients of Alzheimers disease, nongovernmental organizations and the international community. The support for the Alzheimer's Breakthrough Act of 2009 mainly came from the citizens who viewed the act as a breakthrough towards government involvement in finding the cure and apportioning part of the budget towards research for the cure to the disease and welfare support to those affected. The American citizens had a large power base since they had to elect members of congress in future elections .This held the politicians in affix since failure to support the act the politician would be viewed as an ant- reformist legislator to the medical sector which is a crucial sector of the country since it touches on the life of every citizen of the United states (Gingrich Egge, 2007). In the United States the passing of the Alzheimer's Breakthrough Act 0f 2009 received a mixture of reactions from the citizens. For families with people affected and the medical staff involved in the treatment and care of the affected the act was a blessing since the recognition of the Alzheimer's disease as a major problem in the united states .This act had come to assist the researchers with the required monies towards cure which would bring to an end any further suffering to those affected by the Alzheimer's disease in the United states as well as the in other nations which share research information with the United states. In the passing of this act the American law makers put into consideration the less privileged, in terms of health in the American society. This furthered the agenda of equity in the American society through creating a rule that caters for the plight of the patients their caretakers and caters for the research towards the disease. The passing of the Alzheimer's Breakthrough Act 0f 2009 also faced some criticism from the American society concerning the resulting impacts of the research findings once administered on the patients. Some parties viewed the search for the cure of a widely spreading disease in the United States could result to the mutation of the disease causing microorganisms resulting to more resistant strains. There was also some critics who viewed the amount of cash spent on the research of the Alzheimer's disease would strain other sectors of the American society causing undesirable effects to the rest of the population. According to ethical universalism the act is unethical (World Health Organization, 2010). In the American states the policy supports the prevailing norms by encouraging the care of less privileged and the sick in society. This pushes forward the United States agenda of providing equal opportunity to all citizens. This also helps to test the welfare awareness of the government and the level of commitment towards the implementation of policies improving peoples welfare. Alzheimer's breakthrough Act 0f 2009 merges with the current government systems, social and political climate which is mainly aimed at solving the internal problems in the United States as well as solving foreign problems. This has ensured the American legislators have unwavering support from their electorate (Gingrich and Kerrey, 2009). Economic Feasibility Apart from Alzheimers disease being a social burden to the US, it is also an economic one as well. The cost of taking care of an individual suffering from this disease is becoming overwhelming. The minimum level of funding needed to implement this policy is also far over stretching. For the fiscal year 2010, the federal government needed $2, billion, and such sums as may be necessary for each of fiscal years 2011 through 2014. These would be for the purpose of conducting and supporting the research on Alzheimers disease and other related activities as envisaged in under subpart 5 of part C of title IV of the Public Health Service Act (World Health Organization, 2010). The figure stated above is just but the minimum. An estimate as at 2010 showed that it would cost the nation more than $172 billion in health care, long-term care, and hospice services. This funding does not exist in the first place. The number of people providing unpaid care for their loved ones with AAlzheimers is more than 10.9 million. Including g the indirect cost skyrockets the annual cost high enough to potentially bankrupt the nation's entire health care system. In future there would be need to raise more funds from the public to offer support to the failing budget. There is also need to recruit more caregivers as their ratio to that of the patients is disturbing. There would also be need for support from the public in the subsequent years to persuade Congress for additional Alzheimer funding. Administrative Feasibility Part of the plan in the policy was to establish Alzheimers call center. This was meant to provide assistance to the caregivers. The CommentsClose CommentsPermalinkthe call ThhhhthetrjkgkvkeCall Centers are accessible 24 hours a day, 7 days a week, at the national and local levels. Their role is to provide information, care consultation, expert advice and referrals regarding Alzheimers disease. The staffs are professionally trained and this alludes to the overwhelming success thus far. They possess the necessary skills, expertise and the resources as the federal government was to appropriated $1,000,000 for fiscal year 2010, and such sums as may subsequent years through to 2014.CommentsClose CommentsPermalink The staffs are very supportive and passionate towards the delivery of this policy. The challenge is that they are few in number compared to the number of individuals suffering from Alzheimers disease. They are out rightly the best suited for the delivery of the policy since they give individualized attention to each patient. This is evident as there are medical facilities from the national to community level. The caregivers have performed an important role in supporting the patients and with the necessary and sufficient leadership much could be obtained from them. Recommendations The Alzheimer's Breakthrough Act 0f 2009 provided an opportunity for the United States to overcome some of the problems facing the citizens. This act however was not conclusive since the Alzheimer's Breakthrough Act 0f 2009 required re-evaluation to adequately meet the needs of the involved parties in the United States .The recommendations to this policy include; The Alzheimer's Breakthrough Act 0f 2009 requires to re-evaluate the level of funding the government is to provide. This will help find a conclusive solution to the problem hence reduce the economic strain on the United States economy since the cost of Medicare for a patient over the age 65 with the Alzheimer's disease is virtually three times that of a beneficiary devoid of the disease. The increased funds to the Alzheimers disease research might be expensive in the short-run but in the long-run the united states economy will see less of the funds go to Alzheimers Medicare (OTA report, 1987). The United States government should strictly analyze the production of any drug produced from the research findings .This is to ensure the drugs created do not undermine human rights and human dignity. The United States government should ensure all tests carried out do not result to complications in the human mind. The research should also include effects to third parties such as new born babies to parents treated of the drugs developed. This will ensure the new generation of people does not suffer the accumulated effects of the drugs causing more harm than good in the future. Politically such critical analysis of the problem will help create political mileage for the electorate since the legislators will have portrayed responsibility to the American society(World Health Organization, 2010) The United States government organizations should educate the citizens on the findings from the research initiated by the Alzheimer's Breakthrough Act 0f 2009.This will help boost the confidence of the American society. This will happen since the American society will have knowledge on how the funds resulting from the policy directives are being utilized (OTA report, 1987). The Alzheimer's Breakthrough Act 0f 2009 should also include provisions for the creation of specialized institutions to provide specialized care to the Alzheimers patients. This will help improve the quality of services provided towards countering the disease in the United States. The Alzheimer's Breakthrough Act 0f 2009 should also provide for public scrutiny of the effects of the resulting drugs for the disease as well as the components of the curative drugs. This will promote high levels of accountability by the government and drug producer companies. This will translate to improved welfare of the American population. Buy custom Alzheimer's Breakthrough Act 0f 2009 essay

Create a Website Link From a MySQL Database With PHP

Create a Website Link From a MySQL Database With PHP Often people new to working with databases  are able to fetch the information they need and echo it onto a page, but then they struggle with figuring out how to link the results for use on a website. This is a simple process in which you echo the appropriate HTML and call the URL in the middle of it.  You can use PHP to connect to and manipulate databases. The most popular database system used with PHP is MySQL. Together, PHP and MySQL are cross-platform. Create a Link From a MySQL Database With PHP In this example, you fetch an array and assign it to $info, and one of the fields holds email addresses. while($info mysql_fetch_array( $data )) { Print $info[name] . ; Print Note that this code called .$info[email] twice- once to display the email and once to be used in the link. The actual href linking code is placed around the information using print or echo and separated with dots. Here is another example using a web address and website name. while($info mysql_fetch_array( $data )) { Print .$info[sitetitle] . ; } Again you first print the. The URL generated with this code can be used on your website to provide a link to the information contained in the MySQL database.

Ethical aspect in management Assignment Example | Topics and Well Written Essays - 2250 words

Ethical aspect in management - Assignment Example Managers are struggling nowadays to improve the skills of individuals in order to meet the market expectations. As people from all around the world are in contact to do business, therefore unawareness to culture and norms of one another results in unethical practices and values occur in the business environment which results in decrease of trust and eventually huge losses are born by the organizations due to misunderstandings, thus managers have started to make sure that unethical values and practices are not occurring in their organization by using the methods and techniques of management under the light of theories and functions of management. To ensure the standard of ethics in an organization managers have to work hard to set the rules and they have to communicate the code of ethics to each and every employee so that everyone gets the information about the ethical standard which is required to be maintained in the organization. Managers also spend their time to monitor the busine ss carried out in the organization so that employees should develop the sense that they are not at their own to do whatever they want. It is suggested that simply caring for the utility and rights of others and justice while dealing in a business environment ensures that ethical values are being practiced in the organization. (b) Introduction: Management is the ability which is instinctively present in humans however some people are better managers than others because of certain factors which help them polish their ability more than others. Management means different things to different people (Haimann, 1974) but when this term is used in an environment related to business it refers to a process. What is Management' Defining Management The process of planning, decision-making, leading and controlling the available resources of an organization such as man-power, finance, machines and information in order to achieve the organizational goals in the best possible way is called management. Good management results in completion of projects using the resources wisely and in a cost effective manner in accordance with making right decisions and implementing them successfully (Portny, 2007). Management in Modern World Due to its importance in every organization and business environment, management has emerged as an important subject area which is widely studied and practiced all over the world. With the gigantic increase in the population of the world, productivity has emerged as a serious problem in the business organizations because the demand for the product has suddenly increased and despite of having capital and demand of product in the market, organizations are not able to increase their production due to lack of skilled labor (Malhotra, 1997). Therefore, the managers have started to think and search for methods and techniques to fulfill the customer's demand by using the existing labor. Management on this outline is the modern management and in this era managers struggle to improve the performance of the employees individually which in turn results in the improvement in the production of the organization. Management is a complex process because managers have to keep eye on various aspects at the same time therefore

Jet Blue in the United Kingdom Research Paper Example | Topics and Well Written Essays - 1000 words

Jet Blue in the United Kingdom - Research Paper Example As an MNE, Jet Blue also services Aruba, The Bahamas, Puerto Rico, Mexico and Bermuda. Jet Blue is able to compete with much larger U.S.-based airline companies such as American Airlines as the business has been able to shed much of its high operating costs related to supply chain and fleet management by maintaining a lean operations methodology (Jet Blue, 2011). Price reductions in the form of lower and competitive ticket prices are accomplished through its lean business model that makes Jet Blue an attractive alternative to high-frills airline companies. A country where Jet Blue does not have market presence is the United Kingdom, a generally attractive market for foreign direct investment by the organization. The United Kingdom maintains a significant airline infrastructure that will assist Jet Blue in establishing a centralized hub in order to serve the UK market effectively. Major renovations to such airports as Heathrow International have provided more traffic space and feasibi lity for structured and timely arrivals and departures. Alongside the infrastructure exists recent government deregulation of the airline industry that had once controlled pricing and established anti-monopoly legislation by major carriers. This has removed some of the financial and regulatory barriers to new entry by airline competitors, making the United Kingdom a viable market for direct investment. Another advantage of investing in the United Kingdom is the economic environment. Currently, the United Kingdom still measures its currency against the Pound Sterling, a method of isolating volatility and risk associated with the current Eurozone economic crisis related to the Euro. The UK Pound Sterling is currently worth $1.61 as compared to a single U.S. dollar. Jet Blue currently has established a very viable and well-developed supply infrastructure within the United States, giving it many comparative advantages in relation to procurement. By investing in the United Kingdom, Jet B lue can establish a moderately higher pricing structure that is comparative to the British Pound Sterling, providing profit opportunities of approximately 60 percent, especially when moving materials procured in the United States into the foreign UK market where import pricing risks are dramatically reduced compared to this much higher-valued Sterling currency. Procurement costs for on-board operations management will be fundamentally less expensive than in the United States if not procured domestically in the United Kingdom. There is, however, a significant disadvantage to entering the United Kingdom for direct investment. There are currently many different low cost carriers, such as RyanAir and Air Asia, that provide similar low-cost and low-frills options for consumers and business travelers. Deregulation occurring in the last few years has removed entry barriers to these companies that now have high cash flow and considerable positive brand reputation with price sensitive consum ers. Even Virgin Airlines offers similar low-cost methodology allowing this carrier and those such as RyanAir and Air Asia to have comparative and competitive advantages in pricing and quality. Jet Blue is not a well-known brand name in the United Kingdom which could provide much higher cost allocation toward the promotional function (such as advertising and online marketing) in order to compete in this dynamic competitive market. Minimizing foreign exchange risks is not that complicated for Jet Blue, considering the currencies regularly traded in this market. The Euro and the Pound Sterling are both valued much higher than the

Diagnosing and Changing Organizational Culture Personal Statement - 5

Diagnosing and Changing Organizational Culture - Personal Statement Example In the last year, which was my Foundation year, I have learned a good many things. Apart from an insight into subjects like Economics, Business Development, and Accountancy, I developed a spirit of inquiry. I learned how to do proper research through formulating an appropriate research design and methodology, and preparing instruments of data collection. I learned to analyze and interpret data. I have learned how important it is to keep abreast of the current developments in the world and in my field, and have gotten into the habit of regularly reading newspapers. I’ve also learned how important it ma tokes presentations correctly and in a manner that communicates to my target audience. Making presentations is the order of the day in the corporate world. It is not just a skill but is often even taken to the level of an art. Therefore this has been a very valuable competence that I have picked up. I have bettered myself on the general reading front. Besides, both my individual working skills and team working skills have improved a great deal. I have learned that people will always need to work together and that being a team player is as important as working efficiently on an independent basis. I’ve also learned to meet assignment deadlines. In the last year, I created a portfolio containing nine sections, which has been the result of a considerable amount of work throughout the year. The topics that I chose to work on were interesting but they were also challenging - both in terms of depth of detail as well as in dealing with a diverse range of themes. On the research about technology in business, I chose to work on the theme of smartphones. On the research about developments in the energy sector, I chose the oil industry.  

Political Science - State and Society in Europe Essay

Political Science - State and Society in Europe - Essay Example propose a typology that is essentially concerned with cross-national differences that occur in three aspects; these include the association of the state with the market in the provision of welfare, the stratifying impact of welfare states and the value of social rights (Dale 2002). Using cross-national differences that occur along these aspects, Esping-Andersen classified welfare states into three main types. These three types were referred to as the three worlds of welfare: social democratic, liberal and corporatist. The social democratic welfare states encompassed the countries of the Scandinavian region, whereas the liberal welfare states included the countries from the Anglo-Saxon areas. The conservative corporatist welfare state was dominant in Central Europe (Dale 2002). For instance, the German welfare system is considered as a conservative-corporate regime because of its salient social policy features (Cochrane, Clarke & Gewirtz 2001). The three worlds of typology opened new frontiers for the interpretation of comparative welfare state research. The typologies have fueled extensive debate, theoretical criticisms and had led other sociologists to propose their own typologies to understand the social welfare dynamics (Dale 2002). In fact, criticism against the typology surfaced right after the time that the typology was proposed, which has resulted in the development of a series of typologies for welfare states. One of the most significant contributions of the Esping-Andersen typology lies in the fact that it was the first of its kind to initiate the process of researching welfare states from a novel perspective. Before the typology was proposed, much of the research on welfare states was conducted on the comparison between the values of degree outcomes and the quantitative worth of social security expenditures. The essence of the second cluster of welfare state typologies encompasses the connection between paid wor k and welfare as well as the implications

E-waste Essay Example | Topics and Well Written Essays - 750 words

E-waste - Essay Example The technology that has been manufactured for the betterment of the society is now posing a threat as it is being dumped in larger quantities (Luther) This essay will revolve around the concept of E-Waste and how measures are being taken in order to minimize the threat that it poses to the world. E Waste is generally considered a part of the solid waste and is disposed off in the municipal solid waste along with the necessary precautions that need to be taken when disposing it off. This disposal creates a hazard for the society as these gadgets are made up of components that can be hazardous to the health of the individuals (Luther 1-3). The waste that is being disposed off consists of lead, mercury, selenium and other components which are known to be hazardous (Johri 3-4). As these products are being disposed off, the hazardous nature of E-Waste is taking a new leap and the state affairs are taking a keen interest in the aspect of recycling this waste. Many states have already implemented a strategy that forces the concerned authorities to recycle this waste rather than disposing it off. However this recycling has also caused an irk amongst the scholars as the products are being recycled and sent to the developing countries where the hazards of such material increases even further (Luther 1-3). E Waste forms around 0.01% to 1% of municipal solid waste in the developing countries. Televisions and computers that were being built previously consisted of an overwhelming amount of lead. If these computers and televisions are discarded at a ground, these dangerous elements can leak out in the soil and cause havoc. The computer chips and other circuitry are made up of other poisons that can contaminate the soil and this includes mercury which is known to be a cancer causing agent. It is thus very important for the concerned authorities to review the process of dumping this waste and

Research proposal Example | Topics and Well Written Essays - 3750 words

Research Proposal Example cy makers to launch programs on financial support under the administrative powers of Saudi Industrial Development Fund so that loan guarantees are offered to the Saudi banks to engage in feasible lending to the SMEs. The initiatives for providing financial support to the SMEs in Saudi economy have been presented as follows. The small and medium enterprises are such organizations that are comparatively smaller in size and whose employee strength falls below a certain number as designated by the authorities. The categorization of small and medium enterprises have been decided by the authorities like the World Bank, World trade Organization, etc. In the Kingdom of Saudi Arabia, the small and medium enterprises are categorized according to specified criteria designed by the Saudi Industrial Development Fund (Burke and Jarratt, 2004, p.126). The enterprises that earn revenues less than Rls 20 million on an annual basis could be termed as small and medium enterprises in the Kingdom of Saudi Arabia. In order to standardize the criteria for classifying entities as small and medium enterprises, the World Bank has taken responses from the commercial banks in order to remove the differences in classification criteria in several countries. The standardized range that is followed for classifying entities in the cat egory of small enterprises is that the annual sales of the entity should fall with the bracket of Rls 1 lac to Rls 5 million with employee strength of 2 to 49 people. The entities that have annual revenue earnings of Rls 5 million to Rls 50 million and employee strength of 50 to 200 people fall in the category of medium enterprises (Achoui, 2009, p.36). The small and medium enterprises play an important role in the context to economic development. The small and medium enterprises are large in numbers as compared to the large business houses. Although the number of employees employed by the small and medium enterprises is low, the cumulative employment offered by the

E-waste Essay Example | Topics and Well Written Essays - 750 words

E-waste - Essay Example The technology that has been manufactured for the betterment of the society is now posing a threat as it is being dumped in larger quantities (Luther) This essay will revolve around the concept of E-Waste and how measures are being taken in order to minimize the threat that it poses to the world. E Waste is generally considered a part of the solid waste and is disposed off in the municipal solid waste along with the necessary precautions that need to be taken when disposing it off. This disposal creates a hazard for the society as these gadgets are made up of components that can be hazardous to the health of the individuals (Luther 1-3). The waste that is being disposed off consists of lead, mercury, selenium and other components which are known to be hazardous (Johri 3-4). As these products are being disposed off, the hazardous nature of E-Waste is taking a new leap and the state affairs are taking a keen interest in the aspect of recycling this waste. Many states have already implemented a strategy that forces the concerned authorities to recycle this waste rather than disposing it off. However this recycling has also caused an irk amongst the scholars as the products are being recycled and sent to the developing countries where the hazards of such material increases even further (Luther 1-3). E Waste forms around 0.01% to 1% of municipal solid waste in the developing countries. Televisions and computers that were being built previously consisted of an overwhelming amount of lead. If these computers and televisions are discarded at a ground, these dangerous elements can leak out in the soil and cause havoc. The computer chips and other circuitry are made up of other poisons that can contaminate the soil and this includes mercury which is known to be a cancer causing agent. It is thus very important for the concerned authorities to review the process of dumping this waste and

Systematic review critique Essay Example | Topics and Well Written Essays - 1500 words

Systematic review critique - Essay Example There are statements that also include recommendations which are aimed at optimizing the care of patients which are called clinical practice guidelines. These guidelines are supposed to be guided by systematically reviewed evidence and an assessment of harms and benefits of all the alternative options for the care of patients. Rather than offering a one –size-fits-all kind of approach for the care of patient practice guidelines should in theory give an evaluation in terms of quality and precise scientific literature arrived at through extensive research and assessment of the possible harms and benefits of any particular treatment. This kind of information is supposed to enable the providers of health care to continue correctly in the selection the optimum care for each individual patient while taking into consideration their personal preferences. This is highly doubtable due to a large number of reasons in theory and on paper these guidelines should be easy to arrive at and fo llow but that is definitely not the case. The United States congress by the â€Å"Medicare Improvements for Patients and Providers Act of 2008† requested the institute of medicine or IOM to conduct an extensive study of the most suitable methods as used in the development of clinical practice guidelines. Aiming to ensure that organization undertaking the development of these guidelines the suitable approach which would ideally be objective, valid scientifically, reliable and consistent, the IOM put together a committee of experts. This committee came up with eight very ambitious standards for developing the best clinical practices which can be trusted. Whether they succeeded, however is questionable. In as much as their intentions were in the right place it next to impossible to imagine that they would be followed to the letter some of these standards are bound to be sidelined or overlooked in some

Determine Domain and Range Essay Example for Free

Determine Domain and Range Essay the graph by going to the graph window, clicking on File, scrolling down to copy to clipboard and clicking on copy to clipboard. In your opened Word document click on Edit/Paste. Below the pasted graph, answer the following questions. Express your answer using inequalities or interval notation. (1) What is the domain of ? The domain of is the set of all real numbers. (-? , +? ) (2) What is the range of ? The range of is the set of all real numbers greater or equal to zero ( ). [0, +? ) B. On the same graph in Winplot, repeat the procedure above for a new function and add the graph to the previous graph. Copy and paste the new graph into the Word document. Below the new graph, answer the questions below. Express your answer using inequalities or interval notation. (1) What is the domain of ? The domain of is the set of all real numbers. (-? , +? ) (2) What is the range of ? The range of is the set of all real numbers greater or equal to two ( ). [2, +? ) C. Again, on the same graph in Winplot that contains the other two functions, graph a third function . Copy and paste the graph into the Word document. Below the graph answer the questions below. Express your answer using inequalities or interval notation. (1) What is the domain of ? The domain of is the set of all real numbers. (-? , +? ) (2) What is the range of ? The range of is the set of all real numbers greater or equal to minus three ( ). [-3, +? ) D. By observing the answers you have submitted for parts A, B, and C, make a general statement about the domain and range for a function of the type: , for a 0 and also for a 0. The domain of is the set of all real numbers. (-? , +? ) The range of is the set of all real numbers greater or equal to a ( ). [a, +? ) 2. Graphing a Linear Function A. Use Winplot to graph the following linear functions on the same graph. See problem one for how to graph in Winplot and paste the graphs into Word. Copy and paste the graph into the Word document. Below the graph answer the questions shown below. (1) Of the three equations, which has the steeper graph? What is its slope? Of the three equations, has the steeper graph. The slope of is 7/4. (2) What point do all three lines have in common? (Express as an ordered pair. ) All three lines have point (0, 0) in common. B. Use Winplot to graph the following three linear functions on the same graph. Copy and paste the graph into the Word document. Below the graph answer the questions shown below. (1) Compare the graph of the first equation to those of the other two equations. What effect does adding the +1 (second equation) and then the -2 (third equation) have on their graphs as compared to the original graph (first equation )? The graph of equation is parallel to graph of equations and . Adding the +1 to the original graph of , moves graph up by 1 unit. Adding the -1 to the original graph of , moves graph down by 2 unit. (2) Complete the following sentence: The word which best describes the three lines in the graph is _Parallel__. (choose one: perpendicular, intersecting, or parallel. ) (3) What is the slope of each of the three lines? The slope of each of the three lines is ?. (4) What is the y-intercept for each line, respectively? Give the ordered pair for each. The y-intercept for lines , , and are (0,0), (0,1), and (0, -2), respectively. C. Using Winplot, graph the functions y = 3 and y = | x | on the same graph. Copy and paste the graph into the Word document. Below the graph answer the questions shown below. (Enter y = abs(x) into Winplot to graph the second equation). (1) Describe the shape of the graph y = | x |. The shape of the graph is similar to ‘V’. Since y = |x|, therefore the value of y will be always positive and the graph will be represented by equations of two line that forms ‘V’ shape at (0,0). (2) What orientation (horizontal or vertical) does the line y = 3 have? The line y = 3 have horizontal orientation. (3) List the ordered pairs of the 3 points which form a triangle in the picture, (-3, 3), (0,0), and (3,3) (4) Using the formula A = ? bh, what is the area of the triangle pictured? A = (1/2)bh = (1/2)*6*3 = 9 square units. 3. Match the Graph of a Function with its Equation A. Copy and paste all six graphs shown below into your Word document. Label each graph with the appropriate equation from the following list. Use Winplot to help determine the correct match of equation to the given graph.

A Comparison of Schools in the U.S. and Japan Essay -- Essays Papers J

A Comparison of Schools in the U.S. and Japan In Japanese schools, from elementary schools to universities, teachers direct what students should do or how they should be. Students follow the school rules and the directions of teachers. In American schools, on the other hand, students have to be more independent than Japanese students in many ways. Because of differences between Japanese and American schools, Japanese students who begin to study in an American school are shocked, and they take a pretty long time to adjust themselves to the way of American schools. Differences between schools in the two countries are seen in classrooms and during classes: the style of lectures, the relationship between student and teachers, and the style of examinations. First, many Japanese students are surprised by American schools because American students pay much attention to teachers, and also they interrupt teachers to ask questions or to express their opinions. The style of teaching in the U.S. is completely different from Japan, especially in two points. One difference is that teachers in Japan expect students to be quiet in classes. In general, teachers explain the content of textbooks, hand-outs, and other materials. But in American schools, teachers think class participation is very important, and they require students to give their opinions or ask questions in classes. Another difference is that teachers in Japan write down important things on a blackboard, but teachers in the U.S. seldom write everything; they just explain orally. Japanese students are very quiet during classes, and all they do is listen to teachers and copy what teachers write on blackboards. They seldom ask questions during classes but ask friends or teac... ... classes. School systems, including grading systems and examination styles, in Japan and the U.S. are quite different. Also, the relationship between students and teachers is completely different. Most Japanese students who transfer from Japanese schools to American schools, or who go to an American school after they graduate from a Japanese school, may be shocked by the new and different systems and the relationship to their teachers. For Japanese students, the way of American schools seems very difficult--to attend classes, to study, and to understand the system itself--but they also notice that they can study and live to the fullest as a student, as they talk or argue for or against other students or teachers in the classes. Also, they can get satisfaction from learning and understanding every class through the relationship between teachers and other students.

Milton and Cavendish: Faithful Realists :: Paradise lost Blazing World

Milton and Cavendish: Faithful Realists Inquiries regarding the nature and acquisition of knowledge, coupled with the monumental question of whether human beings are capable of accruing knowledge–the philosophical study of epistemology–has roots buried in antiquity: Genesis, to be exact. Great thinkers of the Western tradition have both accepted and rejected components of Old Testament lore; Platonic and Aristotelian philosophers have indeed battled for centuries over the way in which reality is understood. Following Aristotle’s teachings, the empiricists and Enlightenment thinkers regarded the processing of sense and experiential data as the surest way to unlock truth. Plato’s adherents, however, figures such as Immanuel Kant, deemed the human intellect a leaky and misguiding faculty, not quite efficient in comprehending truth. John Milton and Margaret Cavendish, the reigning theological epistemologists of the 17th century, pondered the nature of divine reality, the role of human rationality in understanding God’s master plan, and the means by which that plan is (and should be) grasped by the human race. Both Milton and Cavendish have declared in their works, Paradise Lost and The Blazing World, that reason as a means to arrive at ultimate truth is insufficient; in the end, faith is the only tool with which human beings acquire proper knowledge. After an initial reading of The Blazing World, one would assume Cavendish ranked reason above faith, parting ways with Milton; the Empress in the tale is nearly obsessed with scientific inquiry. Upon close analysis of the text, however, it becomes evident that Cavendish’s message is complementary to Milton’s. This is not to say that either Milton or Cavendish were pure theologians in their world view, placing no value on science or logic; rather, both found a measure of importance in the findings of contemporary science and consequently instilled in their literary protagonists curiosity about the laws of the universe. It was just such cosmic curiosity that plagued thinking individuals of the Renaissance period. As Europe slowly developed a flavor for scientific inquiry, well guarded theological dogmas were threatened; the mid 1600s was indeed a time of questioning long established religious and political doctrines. While grappling with the emerging debate of reason versus faith, Milton and Cavendish offered philosophical fictions heralding the supremacy of the latter. Characters in the authors’ works discover that reason, untempered by belief in divine truth, is dangerous. Cavendish’s Empress of the Blazing World, for example, is a tyrannical ruler who demands that her subjects uncover the secrets of the natural world.

A. E. Housman’s “To An Athlete Dying Young” Essay

E. Housman’s â€Å"To An Athlete Dying Young† is part of his series of poems collected in his book, A Shropshire Lad. It is set during the funeral march of a young and victorious runner who died at the height of his career. The speaker is one of the pallbearers, who recounts the athlete’s victory and philosophizes on the timeliness of his death. As with the rest of the book, this poem resounds with the melancholic themes of death and dying in youth. To be more specific, this poem describes how it is best to die young and at the peak of one’s career in order for one’s memory and legacy to be forever etched in the minds of the people. Though Housman’s exhortation might seem to be bordering on the macabre, it rings true: glory, fortune, and fame are all fleeting. The poem starts by depicting the victory of the runner and how he became the source of pride in his town: â€Å"The time you won your town the race  / We chaired you through the market-place.† The image of chairing shows how the townspeople carried the runner on their shoulders and paraded him in the market-place. The market setting is important, as it depicts a place where people of all ages and social status converge. It is a testament to the runner’s achievement and how it was able to bring together different people together in his victory. As they were carrying him on his shoulder, â€Å"Man and boy stood cheering by, / And home we brought [him] shoulder-high.† The last line of the first stanza foreshadows what would happen as the poem progressed. Carrying him shoulder-high not only indicates how he was chaired by the townspeople but also foreshadows how his coffin would be carried at the same shoulder-high level as he is brought to his tomb. Also, home could be read two ways given the foreshadowing: home as in his physical house and home as in his final resting place. In this manner, the speaker draws a connection between his victory and his death, and how, in both instances, he would be carried by the shoulders to be brought â€Å"home.† In the second stanza, the procession takes a sudden turn from one of gaiety and victory to one of sadness and melancholy, as this time, they are no longer celebrating but sending the athlete to his grave. â€Å"Shoulders† and â€Å"house† again are mentioned, paralleling that of the first stanza albeit taken on a somber tone. The procession takes place on the â€Å"the road all runners come,† a metaphor for the road of life that everyone travels. Another metaphor makes an appearance to further the sober theme: once the athlete has been brought â€Å"home,† he becomes a â€Å"townsman of a stiller town.† The â€Å"stiller town† here refers not only to the cemetery at which he is buried but to the idea that he is resting in peace, that he has accepted his death. Again, this idea of peaceful death corresponds well to the theme. When young people die, people always assume that it is â€Å"untimely,† hence, they cannot rest in peace. However, for the athlete, his death is timely as he is at the peak of his career, ensuring that he will remain a glorious image in the minds of the townspeople for generations to come. The third stanza presents the main theme of the poem by saying that the runner was a â€Å"smart lad, to slip betimes away / From fields where glory does not stay.† The speaker also presents here the laurel as a symbol for glory and the rose as a symbol for the life of non-victors. He compares that lifespan of the laurel to the rose, indicating that the laurel easily withers, while the rose, slow to bloom, lives much longer. The fourth and fifth stanza both expound on the third, as it gives evidence of how death is indeed a blessing for the young athlete, for in death, he is able to preserve his victory. In death, he â€Å"cannot see the record cut,† indicating that he will not have to deal with younger and better runners eventually overtaking him, as they will inevitably do. In dying, too, he will not become like any run-of-the-mill athlete, who did not quit while they were ahead. As such, he is a privileged position, as he will not live to be disgraced, for his body died before his name. In the third stanza, death is represented by the metaphor â€Å"shady night,† which works on an age-old technique of associating death with night. An oxymoron is also used in the third stanza – silence sounds. It marries together two contradictory terms, which furthers the image of death, for in death, the only â€Å"sound† to be heard is â€Å"silence.† The main point of these two stanzas is that the brief life that he had is esteemed, for he did not have to suffer the loss of fame and glory. In the fifth stanza, the athlete is about to be laid in his tomb, and the speaker is exhorting his companions to recount once more the victory. He rationalizes that in doing such an act the memory of the runner’s victory is immortalized, preserving it in the minds of the people. The symbol of the challenge-cup is also used as a testament to the glory of the athlete. Once again, the metaphor of the death as shade is used, indicating that death is not the loss of the light of life but merely the blocking of light. The importance of this metaphor to the poem is that death cannot extinguish the light of the runner’s glory. At most, it can only dim it to a more subtle shadow. Finally, the last stanza elevates the theme of the poem – as well as the glorious athlete – towards another, spiritual level. In a way, the last stanza encapsulates the promise of dying young and at the height of fame, and that despite the seeming â€Å"untimeliness† of his demise, much more is to be gained through death. As the athlete passes on to the next life, the â€Å"strengthless dead† will â€Å"flock to gaze† at his â€Å"early-laurelled head.† The image of the dead surrounding the young athlete (implied by the phrase early-laurelled) is a very powerful one, as it indicates how the glory of the athlete transcends the mortal plane, which makes it an even more laudable success. Furthermore, in this spiritual state, his laurel crowns will not wither. What this means is that his success has finally become immortal, and his glory will no longer fade, preserved as it is, ironically, through death. Death as a way to preserve glory and success may seem to be too vain and too gruesome. However, it is important to go beyond this theme and instead, reach beyond the heart of the poem. For, at its heart and driving spirit is a reminder to people to remember that worldly glory and success are but transitory. Works Cited Housman, A. E. â€Å"To An Athlete Dying Young.† Ed., Untermeyer, Louis. Modern British Poetry. New York: Harcourt, Brace and Howe, 1920; Bartleby.com, 1999. . 12 April 2007.

Spring Jazz Band Concert Report

On Friday, April 29, 2011, I went to see Spring Jazz Concert at Sophia B. Clarke Theater. Most of performers have great instrument skill and show us a wonderful music. Each movement highlights the character, range, and technical abilities of an individual instrument, all of pieces stand on their own as intricate musical gems. The show was divided for two parts, and they have different sections on those two parts.During the concert, we would hear different music programs by playing in different music instruments such as saxophones, trumpets, trombones, drums, bass, guitar, and piano. Each performer represents different music instruments. On the first parts of the concert, there were three songs. In conclusion, I enjoyed this concert very much because the music in this concert was very nice. In my opinion, I had totally different feelings between I listened music in the concert and at home, and the atmosphere of concert was awesome.Besides the music, I had deep impression in the perfor mers; every performers in the concert had much passion when they were performing. In my opinion, because of their wonderful performance, I could hear such nice music. Also, everyone in the concert was polite. Every times when conductor came to the stage or the song was end, almost every audience stood up and applauded to the performers, the applause lasted for a pretty long time. At that time, I felt so good. All in all, I really enjoyed this concert.The tone color of most of the jazz bands that I saw was smooth and inviting. This made the bands easier to listen to. They were polyphonic in structure, where all of the different instruments were playing different melodies. The rhythm that was used was in a quadruple meter. This was true for all of the bands. The only thing that I wished would have happened was that there would have been more improvisation instead of reading from sheet music. They were very structured in that way.

Farmers

Farmer’s discontent during the period 1870 – 1900 had an impact on their attitudes and actions towards national politics. During this time period manufacturing had a huge growth spurt and agricultural began to decline. This made it harder for farmers to make a living. Document G shows how much manufacturing increased between the years 1849 – 1899. America could no longer aspire to be a nation of small freehold farms. Manufacturers and people living in big cities depended on farmers to pretty much keep them alive. Many people didn’t realize how much of an affect farmers had on their everyday lives. If you took farms away from the United States during this period of time, everything would have completely crashed. Farmer’s had difficulties making a living because the rates of being a farmer were so high. â€Å"Nothing has done more to injure the western region than these freight rates. † (Document F) The high rates of being a farmer made it difficult to pay payments on the lands and the rate of interest was rapidly rising. Some farmers couldn’t even sell their produce at a reasonable profit. These farmers worked long, hard hours and the government wasn’t on their side about paying them with a decent income yet they wanted so much from the farmers. Along with farm prices failing, railroad prices were increasing. Railroads were important to farmers because they took farmers out to their lands, carried their produce of hard work to markets, and brought them the manufactured goods that they needed. Many farm settlements were established around railroads because of this reason. Railroad managers were forced to charge very high rates and because of it, that means farmers would have to pay more money to use railroads when they already used enough money keeping their crops alive. Document B talks about how it was also hard for colored farmers to make a living especially after the Civil War. â€Å"They had to get the local merchant or someone else to supply the food for the family to eat while the first crop was being made. (Document B) They couldn’t pay interest and by the end of the first year, they found themselves in debt. The attempt in the second year didn’t go so well either because they had old debts plus new interest to pay. â€Å"Many of the colored farmers had almost given up hope†¦Ã¢â‚¬  (Document B) Not only was money an issue for farmers but also in the late 1880s and early 1890s crop suffered severely from droughts. It was cool and dry which was unfavorable for all crops. This made it difficult for farmers to keep their crops alive. By the late 1880s, farmers were so fed up with everything that they created the Farmers Alliance, seeking to overthrow the chains from the banks and railroads that bound them. The Farmers Alliance merged with other liberal Democrats to form the Populist Party. They strived for railroad regulation, tax reform, and unlimited coinage of silver. In the election of 1892 the Populist Party nominated James B.  Weaver for president and as Document D shows, most of the farmers in the west, mainly Nevada, voted for the Populist Party because that party was rooted in the frustration of the farmers and they needed change. The farmers were furious with the way things were going for them and they had hoped that the Populist Party would help. Even though they didn’t win the election, they made a remarkable showing with 1,029,846 popular votes and 22 electoral votes. These electoral votes only came from the midwestern and western states. With the creation of a new party, out of discontent, the farmers managed to change national politics.

Music Genre Fusion Western Music borrowing from Non-western and Assignment

Music Genre Fusion Western Music borrowing from Non-western and Nonwestern music borrowing from Western Music - Assignment Example As the paper stresses despite this fact, music can’t be apprehended in cultural or societal boundaries and for several decades, musicians from western as well as nonwestern world have been experimenting to combine the western musical traditions with the nonwestern music style and these experiments have eventually produced several masterpieces that represent music fusion genre and gain popularity and appreciation from critics and people from all over the globe (Manuel 98). The term world music has also evolved as a result of these efforts that try to diminish the boundaries between western and nonwestern music through the presentation of well composed infused music pieces. According to the research findings the trend of borrowing music styles from other cultures and societies is by and large regarded as act of open mindedness and empathic gesture of interest since it paves the way towards the creativity and evolution of new music genre that usually possess great appeal for the people of both the societies. From the early sixties to modern day, the western musicians have been attempting to infuse nonwestern musical traditions in their composition and this practice has been adopted by the nonwestern musicians as well who have composed nonconventional music through the bland of western and nonwestern music. The music of Asia and India has especially admired the western musician at large because it has attained its level of perfection and hence, the western musicians find it very fruitful to infuse with the Asian musical traditions.

NHS omputer System Failures Affecting Patient Care Assignment

NHS omputer System Failures Affecting Patient Care - Assignment Example Computers have assisted man ever since their inception. This assignment describes the infusion of Information Technology in the field of health and medicine that has led to the rebirth of the said field. Technological advancements that have affected the field of health were described in the assignment and have affected the human society as a whole directly and have mostly proved to be beneficial rather than hazardous. The researcher focuses on analysis of the NHS OR NATIONAL HEALTH SERVICE that is an organization that was established in UK. The core idea behind the establishment of National Health Services-NHS was to provide high quality of healthcare to all the patients. This was specially intended keeping in mind that no patient should be made to suffer because of his financial stature. Thus apart from very few procedures the NHS unanimously provides medical services to all its patients that are UK residents. Since its inception, there was always one issue or the other that inhibit ed the successful growth of the system, such as the delaying of computerized scheduled patient operations, subscription of timely and accurate medicines, failing to detect and ensure treatment of cancer patients within two weeks and those of emergent nature within four hours. The researcher analyzed and investigated problems, that were mentioned above and provided his own opinion on success of the National Health Services organization as well as some gave some recommendations and solutions found to solve the problems.

Paraphrasing Essay Example | Topics and Well Written Essays - 250 words - 3

Paraphrasing - Essay Example The first reading speed test that I took resulted in a score of 200 words per minute (http://www.readingsoft.com). This score is above average, so it proves that my reading rate is pretty good. The test recommended that I use the FReader software to improve my speed even further. After practicing with this software, I took another test to determine my reading rate (http://learn.eku.edu/webapps/portal/frameset). This website helped me to improve my reading speed considerably. Another website that I used was called Rocket Reader. This assisted me with reading speed, fluency, vocabulary, comprehension, and stamina. I took this test and received a score of 250-350 words per minute, which was above average. However, it told me that I could improve even further, perhaps up to 500 words per minute, after taking more tests on the Rocket Reader website (http://www.speedreaderxreview.com/free-online-reading-speeding-test). I was pleased with my score with this one: 537 words per minute. The analysis showed that I was an above average reader. It said that if I could this speed up consistently then I should have no problem reading this fast when reading casually. The website also recommended other techniques to help my reading rate even further. The last website that I used told me about the different categories of reading rates. Also mentioned was the steps on how to become a fast

Business Plan Research Paper Example | Topics and Well Written Essays - 750 words

Business Plan - Research Paper Example Balance Sheet Basic Template 9.0 Current date: 9.1 Future Dates: 10.0 C: Income Statement Basic Template: 10.0 Marketing current budget revenues: 10.1 Operations current budget expenses: 10.2 Administrative and cost of capital current budget expenses: 11.0 D. ... h interactions with individuals working in the fields in which each child is interested can we encourage and advise each student on what is necessary in school and in life to achieve their goals. Through early interaction we can gain the trust of the students, families and volunteers so to work together to defuse any destructive habits. While working with those individuals in their fields of interest these students will become proteges of these individuals for several years, eventually becoming interns as they get older and closer to their completing course work in that field. Knowledge and Dreams is a program that is in direct response to the growing number of young people falling through the cracks in school and failing to plan for their future. The goal of this program is to offer tutoring of course study and dream development and internship to the youth of the intercity. This program will entangle education before and after adulthood providing professional experience in both area s. The focus is different for every age group although the message is the same, to empower each of them with the knowledge needed to make better decisions for their future. Knowledge and Dreams will focus primarily on intercity youth of all ages. According to the National dropout prevention center â€Å"There are a multitude of youth programs available, but many are inaccessible to inner-city and rural youth (2012, para 2).† Knowledge and Dreams will partner a professional to every group of five who is interested in his/her field of study. These partnerships will last the length of the Childs stay in the program. This program will also provide tutors for these students for each grade level and subject where help is needed. During that time weekly planned activities to strengthen the

MIS {excel project } Assignment Example | Topics and Well Written Essays - 500 words

MIS {excel project } - Assignment Example Additionally; the total quantity of stock is calculated. The sales sheet provides data on sales of the items in stock by the respective customers. The sales are recorded and the total sales are also calculated. The sheet also stores details of the respective customers. The look up function is used in the item column to march the item with its code in the products sheet: =LOOKUP (H4, Products!$A$3:$A$13,Products!$B$3:$B$13). The look up function is also used to determine the price of each item: =LOOKUP ([@[Item Code]],Table1[Code],Table1[Selling Price]). It is in this sheet that the total sales are also calculated and the data sorted according to item code in ascending order. A pivot table called sales summary is generated from the sales sheet. In this sheet, the summary of sales of each item is displayed. The total sales of each item and all the items are totalled. A graph is then generated showing the quantity of items sold. Capital financing analysis is done on the capital financing sheet. In this sheet, the total capital required to establish the business is estimated. A list of possible financing options is also provided together with the percentage of financing. Additionally, the interest rate and the amount to be repaid is

Classical studies Essay Example for Free

Classical studies Essay The Colosseum was the first permanent amphitheatre to be built in Rome. Its huge size, as well as the practical and efficient way it dealt with organising of events and ways of controlling large crowds in a safe manner makes it one of the greatest architectural buildings ever constructed in the Roman Empire and was a gift from Emperor Vespasian and finished under Emperor Titus. The building itself is a vast ellipse with tiers of seating for about 50,000 spectators around a central elliptical arena. There are 76 entrances into the amphitheatre to allow crowds to arrive and leave safely and quickly.  The architects had recognised the need for more permanent seating in the Colosseum as opposed temporary wooden benches or the piles of earth used in previous amphitheatres located in other cities. This was after all the centre of the known world and home to the Emperor and so had to be built on a grand scale never seen before. Firstly it had to be a safe place for people to visit and stay for periods of time. Many revolutionary safety devices were designed and attached to the Colosseum, such as the podiums that were built with top rollers that prevented the wild animals and convicts from climbing on top and into the crowd.  There is also the design of the exterior to consider. Despite the main activity going on inside the theatre, the design of the outside was equally if not more important. What it outwardly showed was very important to the Romans. The games were responsible for ridding the city of criminals and dangerous animals, it had to symbolise great power and splendour. The grand scale of the Colosseum was impressive but not overpowering, it was important that it was welcoming but large enough to entertain audiences in there thousands. PART TWO Essay Although they occupied one of the lowest rungs on the roman society ladder, Gladiators were widely regarded as some of the bravest members of roman society.  A gladiator was considered a professional fighter and apart from fighting other gladiators, would also pit his skills against animals in amphitheatres all over the empire. These battles started out as mere ceremonial bouts at funerals before evolving over 600 or so years into the sort of grand entertainment that we now think of as a typical day in the colosseum or indeed any of the amphitheatres around the republic and empire. The word Gladiator comes from the Latin gladiatores meaning swordsman, which in turn comes from the word gladius which was a short sword used by soldiers in the roman army. Gladiators were usually slaves or prisoners who were bought by a manager and trainer of gladiators (known as a lanista) in order to be trained as proper gladiators. There were also some free men who actually volunteered to be gladiators, no doubt looking for the celebrity that the profession offered successful entrants, a lot like children of today aspiring to becoming a famous footballer or cricketer. There were several different types of gladiators who were trained to excel in the use of different weapons, and wore different types of armour depending on the type of combat they were to enter. Some gladiators who had been prisoners of war used their native weapons and armour, and portrayed themselves as their native characters in battles, such as Gauls or Thracians.  The image often given of the Gladiator as a savage fighter might very well be just fiction. They were very skilled at what they did and like most people they would rather live than die. This is not so the case of criminals who fought and although given training, were not expected to live beyond a year. A gladiator who survived over three years was on occasion set free. It is now thought that fights may have been more civilised and theatrical than previously believed. The level of training these men undertook suggests that they would have been very good at putting on a show for the paying public and controlling movements, in the same way that the wrestlers of today are basically putting on a show. And even if the audience did order a gladiator dead at the conclusion of a match, it is highly probable that the opponent imposed only a superficial wound, in order to please the crowd. The losing gladiator might have then been dragged under the staging area and killed by an executioner undercover or allowed to recover and then resume his occupation a few months later under a new name. After all, it was all about entertaining the masses and making money for both the trainer and the owners of the venues. Because they were such expensive investments, gladiators were allowed the very best food and received the very best medical care available. In most cases Gladiators only fought 3 or 4 times a year so to stay fresh and make a big draw for the crowd who would undoubtedly had favourites from each troop of fighters who would roam from area to area fighting in different amphitheatres month after month. The games though were not only a source of entertainment for the citizens of the Roman empire, but many saw the chance to acquire fame, popularity, a reversal of lost fortunes and even freedom if they were lucky enough to survive. The games were primarily important because of what they offered those involved. Many people profited from the games, in particular those who hosted them. The games conveyed the habits of the upper class, for anyone who hosted the games it was a measure of their wealth as the expense was huge due to the number of beasts and fighters needed to entertain the crowd for any length of time. A new generation of traders and politicians found fame and popularity because they were able to spend great amounts to stage the games, which increased their status and influence within the upper social circle of the roman class system. Because of the way the games were held, it allowed the common people to mix with the upper classes at these events and on occasion win competitions for various luxury items, rather like the 1/2 time golden ticket draw held at most sporting events today. The games were not loved by everyone in roman society. As Cicero questions the measure of enjoyment the games can offer in C7 Pompeys shows, But what pleasure can it be to a man of refinement when either a powerless man is torn by a powerful beast, or else a magnificent beast is spitted on a hunting spear? What he is saying is if youve seen one man kill a beast youve seen it all and vice versa. The gladiator was looked upon as both a hero and a rogue depending on his route into the games and his ability to wow the crowd with his skills as both a warrior and an actor.  In conclusion, the gladiators were important because of what they could offer both the public and the wealthy in respect of status and prestige. The games were also important to Romans because of where they were held and what the amphitheatre conveyed, the very symbol of the politics of Rome.

Low MicroRNA-21 Expression in HPV-Induced Carcinogenesis

Low MicroRNA-21 Expression in HPV-Induced Carcinogenesis Low microRNA-21 expression in the development of a favorable microenvironment for HPV-induced carcinogenesis Introduction Human papillomaviruses (HPVs) are the most common sexually transmitted agents. High risk types of Human Papillomavirus, as HPV16, are the causative agents of virtually all cases of cervical cancer and a significant proportion of other anogenital cancers, as well as some head and neck cancers [1-3]. The K14-HPV16 transgenic mice model is specially used to study the HPV-associated squamous cells cancers. In this model, the expression of early region genes (E2-E8) of HPV-16 is driven by the keratin 14 promoter/enhancer [4]. The K14-HPV16 transgenic mice develop epidermal hyperplastic lesions that progress to dysplastic lesions and ultimately to invasive cancer. The expression of HPV oncogenes E6 and E7 induces epithelial carcinogenesis through well-defined premalignant stages before de novo carcinoma development [5]. The basal cells are mitotically active and thus may develop further mutations in response to a proliferative stimulus, and the expression of K14 has been shown to persist in well-differentiated squamous carcinomas [6]. This model of multistep epithelial neoplasia will facilitate the study of both the epigenetic and the genetic factors that regulate neoplastic progression and coordinate malignant conversion. MicroRNAs (miRNA) are small, noncoding RNAs that regulate gene expression by base pairing with mRNAs, leading to the inhibition of mRNA translation or its degradation. In normal cells, miRNAs control numerous processes including proliferation, differentiation and apoptosis [7]. Furthermore, these molecules are described as key regulators in many diseases including, neurological disorders, cardiovascular diseases, viral infections and cancer. Some miRNAs are lost during tumorigenesis whereas other miRNAs are upregulated. Previous data indicates that miRNAs are important to distinguish subtypes of cancers, where the histological diagnosis is complex and difficult. Furthermore, it also may be a useful tool to diagnose cancers of unknown origin and to study cancer predisposition [8]. MicroRNA-21 (miR-21) has been implicated in various aspects of carcinogenesis. In most solid tumors, miR-21 is overexpressed and thus influences cell proliferation, differentiation and apoptosis [9-11]. However, the interplay between miRNAs, human papillomavirus (HPV) genes and how these interactions contribute to HPV-associated cancers remain elusive and not well understood. The tumor microenvironment associated to miRNAs plays an increasingly appreciated role in cancer (ref whiteside) however, the microenvironment prior to tumorigenesis can influence the carcinogenesis process. In this study we investigated the expression profile of microRNA-21 in K14-HPV16 transgenic mice, using ear and chest skin samples. Thus, we evaluate the importance of the microenvironment associated with the miR-21 expression and predisposition to HPV-induced carcinogenesis. Material and methods Transgenic mice K14-HPV16 mice on a FVB/N background were generously donated by Drs. Jeffrey Arbeit and Douglas Hanahan, from the University of California, through the USA National Cancer Institute Mouse Repository. Generation of K14-HPV mice has been previously reported [12]. After one week quarantine, the animals were kept as breeder pairs in accordance with National (Portaria 1005/92 dated October the 23rd) and European (EU Directive 2010/63/EU) legislation, under controlled conditions of temperature (23 ±2 ºC), light-dark cycle (12h light/12h dark) and relative humidity (50 ±10%), using hardwood bedding. A standard diet (Global Diet 2014, Harlan, Barcelona) and water were provided ad libitum. Health checks were performed daily. Genotyping of HPV-E6 and E2 (referencias genotipagem Hugo?) 15 offspring females from consecutive litters were genotyped at weaning, using tail tip samples. To genotyping were used tail tips of mice of the strain FVB, wild-type or hemizygous. Tissue lysis was performed using MAGNAPure DNA Tissue Lysis Buffer and Proteinase K for 17 h at 65  °C. Nucleic acids were extracted by the High Pure Viral Nucleic Acid Kit following the manufacturers instructions. To test the efficacy of the method of DNA extraction was investigated the presence of mouse-ÃŽ ²-globin gene. The presence of integrated HPV was assessed by amplification of HPV-E6 and HPV-E2 genes by polymerase chain reaction methodology (PCR) in-house. The resulting genotypes were confirmed to the respective phenotypes. After genotype determination, all animals were sacrificed at 22 to 26 weeks-old and completely necropsied. Ear and chest skin samples were collected into TRIzol (Invitrogen) for miRNA analysis and matched samples were collected into 10% neutral buffered formalin for histological processing. For these procedures, 13 skin samples (ear and chest) of 8 hemizygous females (+ / -) were collected. As control were used 14 skin samples of 7 wild-type females (- / -). Histology Skin samples were fixated in 10% neutral buffered formalin for 48 hours, routinely processed and paraffin-embedded. Histological sections (2 µm-thick) were obtained and stained with haematoxylin and eosin (HE) for examination on light microscopy. Samples and their lesions were classified as normal skin, epidermal hyperplasia and epidermal in situ carcinoma by two independent, blind researchers (CL and RGC). miRNA expression analysis To study miRNA-21 expression, the skin samples were macerated with the TRIzol reagent (Invitrogen) for RNA preservation. The extraction of total RNA was performed using aHigh Pure RNA Isolation Kit(Roche Applied Science), according to manufacturer’s instructions. RNA quality was assessed by measuring the absorbance at 260 nm and its purity was evaluated by the ratio of absorbance at 260/280 nm. cDNA synthesis The conversion of miRNA to cDNA was performed using TaqMan ® MicroRNA Reverse Transcription Kit ( PN 4366596 , Applied Biosystems ®, Foster CA, USA ), using sequence-specific stem-loop primers from each miRNA (miR-21 and snoRNA-202). The amplification conditions were as follows: 30 min at 15 °C, 52 min at 42 ºC and finally 10 min at 85 °C. miRNA-21 relative quantification We used qPCR technique to measure the relative expression of miR-21 (StepOne Real-time PCR Systems; final volume: 20 uL, with1Ãâ€" TaqMan ® Universal Master Mix II Applied Biosystems, Foster City, California USA; 1x MicroRNA Assay (Applied Biosystems, Foster City, California USA) and 2 uL cDNA. As endogenous control, we used snoRNA-202. Statistical Analysis Data analysis was performed by the computer software IBM ®SPSS  ®Statistics for Windows (Version 20.0). The 2ΔΔCt method, along with Student’s t-test was used in order to evaluate any statistical differences in the normalized expression of the miR-21. To analyze the normalized relative expression (-ΔCt) of the different groups, we considered the results corresponding to 99% representation of the population ( ±2).      Results Genotyping and histological analysis We observed the presence of integrated HPV DNA (E6 and E2 ORF) in 53% of mice. All cases with HPV-E6 expression also presented HPV-E2 expression. All mice with integrated HPV DNA demonstrated, phenotypically, various degrees of persistent epidermal and squamous mucosal hyperplasia, characteristic lesions associated to HPV infection, previously described in Arbeit et al. study [12]. After histologic evaluation we observed that, in all cases with integrated HPV DNA, the ear tissues presented epidermal in situ carcinomas while the chest tissues showed epidermal hyperplasia. In wild-type mice we observed normal histology. MiRNA-21 expression profile in tissue of transgenic versus wild-type mice To investigate a possible direct influence of HPV16 on the miR-21 expression profile, we analyzed the relative expression between the all tissues (ear and chest) of transgenic mice and the tissues of the control group. We did not found statistical difference in expression levels between both groups (p=0,615). When we compare the miRNA-21 expression in ear and chest samples, singly, we also did not found statistical difference in expression levels between transgenic and wild type mice (Fig.2). MiRNA-21 expression profile in normal tissue To study the miR-21 normal expression profile in tissues, we quantified the expression of miR-21 in the ear and chest skin samples of the control group. We observed that the ear tissues have lower expression levels when compared to chest tissue (p = 0.036) (Fig.3 a)). Mir-21 expression profile in tissues of transgenic mice To compare the relation between miR-21 expression and lesion type, we analyzed the histology of ear and chest samples from transgenic mice and we quantified the expression of miR-21 in the same. We detected that lower expression levels of miR-21 are associated with cancerous lesions as in situ carcinomas (ear) compared with hyperplastic lesions (chest) (p=0,043) (Fig.3 b)). Discussion Recent studies have associated miR-21 to the pathogenesis of various diseases, including cancer. (ref) MiR-21 overexpression is observed in the majority of carcinomas and hematological malignancies. However, understanding of the potential role of miRNA-21 in previous microenvironment to the development of HPV-associated lesions remains elusive. In cervical cancer, it is accepted that HPV infection is the most important factor for transition from normal cervical epithelium to cervical pre-neoplastic intraepithelial neoplasia and subsequently to invasive cervical cancer. However, the influence of others factors including the microenvironment are poorly investigated. Microenvironment associated to miR-21 may be key factor to the predisposition of cancer. We studied that the expression of miR-21 in normal tissues could be important in development of HPV-associated tumors. Our results demonstrate that, in transgenic mice, all ear tissues presented epidermal in situ carcinomas and chest tissues showed epidermal hyperplasia. Thus, we hypothesize that these interesting facts could be related to different miR-21 profile expression of both tissues. Our results indicate that there is no statistically significant difference between the miR-21 expression in HPV-positive samples and controls, concluding therefore that the presence of HPV does not directly influence the expression of this microRNA. This result is consistent with the hypothesis that differences in the miR-21 expression existing in the normal tissue microenvironment are an important determinant of the HPV-induced carcinogenesis process. Several studies have expanded the concept that inflammation is a critical component of tumour progression. Many cancers arise from sites of infection, chronic irritation and inflammation [13]. Thomas X. Lu et al., identified an IL-12/IFN-g–dependent pathway as the most prominent upregulated pathway in the lungs of OVAchallenged miR-21-/- mice compared with wild-type littermate controls, providing substantial evidence that this is the major pathway dysregulated in the miR-21–deficient mice [14]. As IL-12 is a major cytokine that regulates Th1 versus Th2 decisions primarily by inducing T cells to produce the Th1 cytokine IFN-ÃŽ ³ [15], may be related to inflammation responsible for tumor progression. These facts that relate the miR-21 downregulation with increased inflammation may explain our findings that tissues with lower miR-21 expression are more likely to develop a carcinogenic pathway. Pten has been verified as a miR-21 target in pancreatic cancer, hepatocellular cancer and squamous cell carcinoma [16, 17]. (†¦) References 1.Walboomers, J.M., et al., Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol, 1999. 189(1): p. 12-9. 2.Watson, M., et al., Using population-based cancer registry data to assess the burden of human papillomavirus-associated cancers in the United States: overview of methods. Cancer, 2008. 113(10 Suppl): p. 2841-54. 3.Major, T., et al., The characteristics of human papillomavirus DNA in head and neck cancers and papillomas. J Clin Pathol, 2005. 58(1): p. 51-5. 4.Coussens, L.M., D. Hanahan, and J.M. Arbeit, Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice. Am J Pathol, 1996. 149(6): p. 1899-917. 5.Masset, A., et al., Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor. Int J Cancer, 2011. 128(2): p. 283-93. 6.Stoler, A., et al., Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation. J Cell Biol, 1988. 107(2): p. 427-46. 7.Chen, C.Z., MicroRNAs as oncogenes and tumor suppressors. N Engl J Med, 2005. 353(17): p. 1768-71. 8.Paranjape, T., F.J. Slack, and J.B. Weidhaas, MicroRNAs: tools for cancer diagnostics. Gut, 2009. 58(11): p. 1546-54. 9.Chan, J.A., A.M. Krichevsky, and K.S. Kosik, MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res, 2005. 65(14): p. 6029-33. 10.Iyevleva, A.G., et al., High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas. Breast Cancer Res Treat, 2012. 131(3): p. 1049-59. 11.Kulda, V., et al., Relevance of miR-21 and miR-143 expression in tissue samples of colorectal carcinoma and its liver metastases. Cancer Genet Cytogenet, 2010. 200(2): p. 154-60. 12.Arbeit, J.M., et al., Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice. J Virol, 1994. 68(7): p. 4358-68. 13.Coussens, L.M. and Z. Werb, Inflammation and cancer. Nature, 2002. 420(6917): p. 860-7. 14.Lu, T.X., et al., MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity. J Immunol, 2011. 187(6): p. 3362-73. 15.Gately, M.K., et al., The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses. Annu Rev Immunol, 1998. 16: p. 495-521. 16.Darido, C., et al., Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell, 2011. 20(5): p. 635-48. 17.Meng, F., et al., MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology, 2007. 133(2): p. 647-58. Fig. 1 Mice genotyping. The presence of integrated HPV was assessed by amplification of HPV-E2 (b) and HPV-E6 (c) genes by polymerase chain reaction methodology (PCR) in-house. Mouse-ÃŽ ²-globin gene was used as endogenous control (a). Fig. 2 Normalized relative expression of miR-21 in transgenic mice (HPV+) and wild-type mice (HPV-), in ear (a) and chest tissue (b). 1